Antibiotics are one of the foundations of modern medicine. Every year, roughly one in three people worldwide rely on them to treat common bacterial infections. They are also essential for the hundreds of millions who undergo surgery, receive chemotherapy, or need an organ transplant each year. Yet the effectiveness of these life-saving medicines is increasingly threatened as antibiotic resistance continues to spread.
AMR is a leading and growing cause of mortality worldwide.
In 2021, bacterial infections were associated with 4.71 million deaths, including 1.14 million deaths directly attributable to antibiotic resistance.
Without intervention, AMR-attributable deaths across all bacterial pathogens are projected to exceed 1.91 million annually by 2050.
The development of new antibiotics is necessary, but it is slow and expensive. Public health and stewardship strategies are helping, but they can’t keep up.
What if we could use epidemiological methods to detect, model, design and test interventions that prevent or slow the movement and exchange of resistance in bacterial networks?
Resistance Networks asks whether plasmid-mediated transmission of resistance can be measured, modeled, and interrupted. By reducing the growth of resistance prevalence to current antibiotics, and stopping its emergence in new ones, Resistance Networks – alongside new antibiotics – could avert more than 464,000 deaths a year from resistant E. coli and Klebsiella alone by 2050.
Proposal submissions for Resistance Networks will be accepted between August 29 - September 4
Proposal application steps
- Download Guidelines
- Download Funding and Activities Summary Template
- Upload your proposal and submit your application before September 4th at 11:59pm ET.
Resistance Networks
Antibiotics are one of the foundations of modern medicine. Every year, roughly one in three people worldwide rely on them to treat common bacterial infections. They are also essential for the hundreds of millions who undergo surgery, receive chemotherapy, or need an organ transplant each year. Yet the effectiveness of these life-saving medicines is increasingly threatened as antibiotic resistance continues to spread.
AMR is a leading and growing cause of mortality worldwide.
In 2021, bacterial infections were associated with 4.71 million deaths, including 1.14 million deaths directly attributable to antibiotic resistance.
Without intervention, AMR-attributable deaths across all bacterial pathogens are projected to exceed 1.91 million annually by 2050.
The development of new antibiotics is necessary, but it is slow and expensive. Public health and stewardship strategies are helping, but they can’t keep up.
What if we could use epidemiological methods to detect, model, design and test interventions that prevent or slow the movement and exchange of resistance in bacterial networks?
Resistance Networks asks whether plasmid-mediated transmission of resistance can be measured, modeled, and interrupted. By reducing the growth of resistance prevalence to current antibiotics, and stopping its emergence in new ones, Resistance Networks – alongside new antibiotics – could avert more than 464,000 deaths a year from resistant E. coli and Klebsiella alone by 2050.
Proposal submissions for Resistance Networks will be accepted between August 29 - September 4
Proposal application steps
- Download Guidelines
- Download Funding and Activities Summary Template
- Upload your proposal and submit your application before September 4th at 11:59pm ET.